Brain metastasis from prostate small cell carcinoma: not to be neglected.
Can J Neurol Sci
; 29(4): 375-7, 2002 Nov.
Article
en En
| MEDLINE
| ID: mdl-12463494
ABSTRACT
BACKGROUND:
Symptomatic brain metastases from prostatic carcinoma are rare (0.05% to 0.5%). CASE REPORT A 70-year-old man presented with a homonymous hemianopsia due to brain metastatic prostatic carcinoma shortly before becoming symptomatic of prostatic disease. CT and MRI of the brain showed a tumour deep in the right hemisphere near the thalamus and involving the optic radiation.RESULTS:
Routine haematological and biochemical tests were normal. The prostate specific antigen level was low on two separate occasions. The prostatic and brain tumours showed identical appearances, namely of a poorly differentiated adenocarcinoma with neuroendocrine differentiation (small cell carcinoma).CONCLUSION:
A literature review suggests that small cell carcinoma of the prostate is more likely to spread to the brain compared to adenocarcinoma and that brain metastases indicate a poor prognosis. The prostate gland should be remembered as a possible cause of brain metastases and that a normal serum prostate specific antigen does not exclude this diagnosis.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias de la Próstata
/
Neoplasias Encefálicas
/
Carcinoma de Células Pequeñas
Tipo de estudio:
Prognostic_studies
Límite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Can J Neurol Sci
Año:
2002
Tipo del documento:
Article
País de afiliación:
Países Bajos