[Soluble receptors of TNF-alpha with molecular mass 55 kDa in rheumatoid arthritis: clinical role]. / Rastvorimye retseptory FNOalfa s molekuliarnoi massoi 55 kDa pri revmatoidnom artrite: klinicheskoe znachenie.
Klin Med (Mosk)
; 81(4): 42-6, 2003.
Article
en Ru
| MEDLINE
| ID: mdl-12785223
ABSTRACT
UNLABELLED To evaluate clinical implications of the serum level of soluable receptors of tumor necrosis factor alpha (TNFa) with molecular mass 55 kDa (rTNF-55R) in rheumatoid arthritis, serum levels of rTNF-55R and rTNF-75R were measured with the use of radioimmunoassay in 76 RA patients, 38 donors and in 25 RA patients, 10 donors, respectively. RESULTS:
Elevated serum level of rTNF-55R was recorded in 55.3% RA patients. This level correlated with basic clinical and laboratory parameters of RA, the disease activity, values of DAS indices. It is concluded that a serum level of rTNF-55R adequately reflects clinico-laboratory activity of RA and its measurement can be used for assessment of RA activity and treatment efficiency.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Artritis Reumatoide
/
Inmunoglobulina G
/
Antígenos CD
/
Receptores del Factor de Necrosis Tumoral
Límite:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Ru
Revista:
Klin Med (Mosk)
Año:
2003
Tipo del documento:
Article