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Developing human erythroid cells grown in transferrin-free medium utilize iron originating from extracellular ferritin.
Leimberg, J M; Konijn, A M; Fibach, E.
Afiliación
  • Leimberg JM; Department of Human Nutrition and Metabolism, Faculty of Medicine, The Hebrew University, Jerusalem, Israel.
Am J Hematol ; 73(3): 211-2, 2003 Jul.
Article en En | MEDLINE | ID: mdl-12827660
ABSTRACT
In addition to transferrin, ferritin can also function as a source of iron for heme synthesis (Gelvin D, et al. Blood 1996;883200-3207; Meyron-Holtz EG, et al. Blood 1999;943205-3211). In the present study we investigate the effect of external ferritin on the proliferation and hemoglobinization of human erythroid precursors grown in transferrin-free cultures.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Precursoras Eritroides / Ferritinas / Hierro Límite: Female / Humans / Pregnancy Idioma: En Revista: Am J Hematol Año: 2003 Tipo del documento: Article País de afiliación: Israel
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Precursoras Eritroides / Ferritinas / Hierro Límite: Female / Humans / Pregnancy Idioma: En Revista: Am J Hematol Año: 2003 Tipo del documento: Article País de afiliación: Israel
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