Plasma total homocysteine level in mothers of children with clubfoot.
J Pediatr Orthop
; 23(5): 658-60, 2003.
Article
en En
| MEDLINE
| ID: mdl-12960632
ABSTRACT
The pathogenesis of clubfoot is unknown despite numerous hypotheses. To clarify the relationship between the plasma total homocysteine level and congenital idiopathic clubfoot, blood samples from mothers of children with congenital idiopathic clubfoot (group 1) and mothers of children without congenital anomaly (group 2) were studied. Groups were the same for factors affecting the plasma total homocysteine level. Mean plasma total homocysteine level was 16.34+/-4.78 micromol/L in group 1 and 11.02+/-1.85 micromol/L in group 2, and there was significant statistical difference between the groups (P<0.05). Congenital idiopathic clubfoot showed a significant association with high plasma total homocysteine level. This study may be a step toward clarification of clubfoot pathogenesis.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Pie Equinovaro
/
Homocisteína
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Child
/
Female
/
Humans
Idioma:
En
Revista:
J Pediatr Orthop
Año:
2003
Tipo del documento:
Article
País de afiliación:
Turquía