[The effect of carnosine on hematopoietic stem cell activity in irradiated animals]. / Vliianie karnozina na aktivnost' gemopoéticheskikh stvolovykh kletok u obluchennykh zhivotnykh.

ABSTRACT

Carnosine given to adult animals together with potable water one day prior to gamma-irradiation or injected in a single intraperitoneal dose one hour after irradiation enhances colony formation by haemopoietic stem cells migrating from the bone marrow to the spleen. In young animals with a high colony-forming activity carnosine either decreases or does not influence at all the efficiency of colony production.