Treatment of exogenous ochronosis with a Q-switched alexandrite (755 nm) laser.
Dermatol Surg
; 30(4 Pt 1): 555-8, 2004 Apr.
Article
en En
| MEDLINE
| ID: mdl-15056151
ABSTRACT
BACKGROUND:
Exogenous ochronosis is a cutaneous disorder characterized by blue-black or slate-gray hyperpigmentation resulting from the prolonged use of certain topical agents, most commonly hydroquinones. It is notoriously difficult to treat.OBJECTIVE:
To report the effectiveness of a quality-switched (QS) 755-nm alexandrite laser in treating hydroquinone-induced exogenous ochronosis.METHODS:
Hydroquinone-induced exogenous ochronosis in two patients was treated with a QS alexandrite laser. The first patient received six treatments (average fluence=7.8 J/cm(2)) at 2-month intervals. The second patient received four treatments (average fluence=6.9 J/cm(2)) at 4-month intervals. Biopsies of lesional skin were obtained before and after laser treatment for histologic evaluation.RESULTS:
Significant lightening of the pigmented skin areas was achieved in both patients without scarring or textural changes. Decreased dermal pigmentation was observed on histologic examination of treated skin specimens.CONCLUSION:
The QS alexandrite laser can effectively treat exogenous ochronosis without untoward side effects.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hiperpigmentación
/
Fármacos Dermatológicos
/
Terapia por Láser
/
Hidroquinonas
/
Ocronosis
Límite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Dermatol Surg
Asunto de la revista:
DERMATOLOGIA
Año:
2004
Tipo del documento:
Article
País de afiliación:
Estados Unidos