[Efficacy of weekly administration of paclitaxel for advanced or recurrent gastric cancer with peritoneal dissemination].
Gan To Kagaku Ryoho
; 31(5): 759-61, 2004 May.
Article
en Ja
| MEDLINE
| ID: mdl-15170988
ABSTRACT
We report 3 gastric cancer patients with peritoneal dissemination who failed to take TS-1 due to adverse effects and who were successfully treated with weekly paclitaxel administered intravenously. The patients were 2 men and 1 woman from 73 to 82 years in age. The histological types of gastric cancer were undifferentiated adenocarcinoma in all cases. Intravenous infusion of TXL (62-80 mg/m2) after short premedication was continued for 3 weeks followed by 1 week rest. Clinical symptoms, including ascites and intestinal obstruction, improved only after administration of 1 cycle in all patients. Except for 1 event with grade 3 neutropenia, no major adverse reactions were observed. Weekly administration of paclitaxel may be a promising chemotherapy for controlling peritoneal metastasis and improving the quality of life of patients with advanced or recurrent gastric cancer.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Peritonitis
/
Neoplasias Gástricas
/
Adenocarcinoma
/
Paclitaxel
/
Antineoplásicos Fitogénicos
Aspecto:
Patient_preference
Límite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Idioma:
Ja
Revista:
Gan To Kagaku Ryoho
Año:
2004
Tipo del documento:
Article