[Effects of positive end-expiratory pressure on lung recruited volume and oxygenation in patients with acute respiratory distress syndrome].
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
; 16(7): 399-402, 2004 Jul.
Article
en Zh
| MEDLINE
| ID: mdl-15238174
ABSTRACT
OBJECTIVE:
To access alveolar recruitment with positive end-expiratory pressure (PEEP) and to correlate the recruited volume with arterial oxygenation in acute respiratory distress syndrome (ARDS).METHODS:
Eleven ventilated patients satisfying criteria of ARDS were included in the study group. Recruited volume of three different PEEP levels [5 cm H2O, 10 cm H2O, 15 cm H2O (1 cm H2O=0.098 kPa)] were measured by pressure-volume curve method. Effects of different PEEP levels on lung mechanics and gas exchange were compared.RESULTS:
Lung recruited volume elevated when PEEP increased from 5 cm H2O to 15 cm H2O[(40.2+/-15.3)ml vs. (123.8+/-43.1)ml vs. (178.9+/-43.5)ml, all P<0.05]. Arterial oxygenation index increased with PEEP and a positive correlation was found between recruited volume and changes in arterial oxygenation index (r=0.483, P<0.01). There was no significant difference during the static compliance at different PEEP levels at a fixed tidal volume (P>0.05). Recruited volume at PEEP 15 cm H2O in the patient group with lower inflection point (LIP) was larger than the group without LIP.CONCLUSION:
Recruited volume increases with PEEP, and the PEEP-induced increase in arterial oxygenation is significantly correlated to recruited volume.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndrome de Dificultad Respiratoria
/
Respiración con Presión Positiva
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Revista:
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
Asunto de la revista:
MEDICINA DE EMERGENCIA
/
TERAPIA INTENSIVA
Año:
2004
Tipo del documento:
Article
País de afiliación:
China