[Effects of immunomodulating therapy on immune status and the disease course in patients with relapsing herpetic stomatitis]. / Vliianie immunomoduliruiushchei terapii na immunnyi status i techenie zabolevaniia u bol'nykh s retsidiviruiushchim gerpeticheskim stomatitom.
Stomatologiia (Mosk)
; 83(5): 20-3, 2004.
Article
en Ru
| MEDLINE
| ID: mdl-15477835
ABSTRACT
Clinical and immunological efficiency of leukinferone in combination with polyoxidonium (immunomodulator) was studied in patients with relapsing herpetic stomatitis (RHS). The levels of alpha- and gamma-IFN were decreased, levels of IgM, IgG, and IgE were increased, active oxygen forms were actively produced, and the count of CD8(+)-cells was increased in patients with RHS. Treatment with polyoxidonium and leukinferone led to an increase of the blood levels of alpha- and gamma-IFN, decrease of IgM, IgG, and IgE levels, normalization of phagocytosis, and decrease of CD8(+)-cell count. The treatment had a pronounced clinical effect in patients with RHS of any severity, which indicates the efficiency of these drugs in combined therapy of patients with RHS.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Estomatitis Herpética
/
Interferón Tipo I
/
Adyuvantes Inmunológicos
/
Citocinas
Tipo de estudio:
Prognostic_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Ru
Revista:
Stomatologiia (Mosk)
Año:
2004
Tipo del documento:
Article