Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometry.
Genome Biol
; 6(1): R9, 2005.
Article
en En
| MEDLINE
| ID: mdl-15642101
ABSTRACT
A crucial aim upon the completion of the human genome is the verification and functional annotation of all predicted genes and their protein products. Here we describe the mapping of peptides derived from accurate interpretations of protein tandem mass spectrometry (MS) data to eukaryotic genomes and the generation of an expandable resource for integration of data from many diverse proteomics experiments. Furthermore, we demonstrate that peptide identifications obtained from high-throughput proteomics can be integrated on a large scale with the human genome. This resource could serve as an expandable repository for MS-derived proteome information.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Péptidos
/
Espectrometría de Masas
/
Genoma Humano
/
Proteoma
/
Bases de Datos de Proteínas
/
Proteómica
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Genome Biol
Asunto de la revista:
BIOLOGIA MOLECULAR
/
GENETICA
Año:
2005
Tipo del documento:
Article