Effects of compounds in leaves of Salix matsudana on arachidonic acid metabolism.
Yakugaku Zasshi
; 125(12): 1005-8, 2005 Dec.
Article
en En
| MEDLINE
| ID: mdl-16327246
ABSTRACT
Apigenin 7-O-beta-D-glucopyranuronide (1), luteolin 7-O-beta-D-glucopyranuronide (2), m-hydroxybenzyl beta-D-glucoside (3), and chrysoeriol 7-O-beta-D-glucopyranuronide (4) were isolated for the first time from the leaves of Salix matsudana. Furthermore, the effects of compounds 1, 2 and 3 on arachidonic acid metabolism were studied. These compounds inhibited significantly the production of 12-hydroxy-5, 8, 10, 14-eicosatetraenoic acid (12-HETE). In addition, the aglycon apigenin inhibited not only 12-HETE but also thromboxane B(2) (TXB(2)). The effect of compound (4) on arachidonic acid metabolism is now under investigation.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plaquetas
/
Ácido Araquidónico
/
Hojas de la Planta
/
Salix
/
Apigenina
/
Luteolina
/
Glucósidos
Límite:
Animals
Idioma:
En
Revista:
Yakugaku Zasshi
Año:
2005
Tipo del documento:
Article
País de afiliación:
China