[The state of health of oncology nurses characterized by genetic and immunotoxicologic biomarkers]. / Citosztatikumokkal exponált nôvérek egészségi állapotának jellemzése gén- és immuntoxikológiai módszerekkel.
Magy Onkol
; 50(2): 153-61, 2006.
Article
en Hu
| MEDLINE
| ID: mdl-16888679
ABSTRACT
Statistical data indicate a chronic shortage of work-force due to overwork, ill health state and increased risk of chronic noninfectious diseases in Hungarian health care personnel, which needs investigations in order to decrease the risk. Nurses of oncology units, often exposed to carcinogens when preparing and handling cytostatic drugs, are especially at high risk. In the present publication we report a complex clinical, geno- and immunotoxicology risk assessment of altogether 500 nurses, performed during the last 10 years at various oncology units in Hungary. The obtained results indicate that the health status of nurses at oncology units is better than the Hungarian average, especially of hypertonia and type II diabetes. However, the prevalence of iron deficiency anemia and different thyroid gland diseases is significantly higher than those of the controls matched for sex and age. The results suggest that iron deficiency can potentiate the resistance to insulin, i.e. the persistence of iron deficiency may increase the serum glucose levels and thus the risk of diabetes. Among the studied geno- and immunotoxicology biomarkers, the frequency of chromosome aberrations, sister chromatid exchange and B lymphocytes was significantly increased compared to the matched controls. The obtained alterations demonstrate the occupational exposure of the nurses to cytostatic drugs, thus the introduction of more strict hygienic controls and compliance with the European Union chemical safety regulations is necessary.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermería Oncológica
/
Enfermedades de la Tiroides
/
Estado de Salud
/
Exposición Profesional
/
Anemia Ferropénica
/
Antineoplásicos
/
Enfermeras y Enfermeros
/
Enfermedades Profesionales
Tipo de estudio:
Guideline
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Aspecto:
Determinantes_sociais_saude
/
Patient_preference
Límite:
Adult
/
Female
/
Humans
País/Región como asunto:
Europa
Idioma:
Hu
Revista:
Magy Onkol
Asunto de la revista:
NEOPLASIAS
Año:
2006
Tipo del documento:
Article
País de afiliación:
Hungria