Improved production of pristinamycin coupled with an adsorbent resin in fermentation by Streptomyces pristinaespiralis.
Biotechnol Lett
; 28(22): 1811-5, 2006 Nov.
Article
en En
| MEDLINE
| ID: mdl-16912920
ABSTRACT
Batch fermentation by Streptomyces pristinaespiralis with the addition of adsorbent resins was used to increase the production of pristinamycin. In consideration of the adsorption capacity and the desorption ability, a polymeric resin, JD-1, was finally selected. The maximum production of pristinamycin in Erlenmeyer flasks went up to 1.13 from 0.4 g l(-1), by adding 12% (w/v) resin JD-1 into the culture broth at 20 h after inoculation. In a 3 l bioreactor, pristinamycin fermentation with the addition of 12% (w/v) resin JD-1 at 20 h after inoculation reached 0.8 g l(-1), which was a 1.25-fold increase over fermentation without resin.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Resinas de Plantas
/
Streptomyces
/
Biotecnología
/
Reactores Biológicos
/
Pristinamicina
/
Fermentación
/
Antibacterianos
Idioma:
En
Revista:
Biotechnol Lett
Año:
2006
Tipo del documento:
Article