Protein dynamics and function: insights from the energy landscape and solvent slaving.
IUBMB Life
; 59(8-9): 506-12, 2007.
Article
en En
| MEDLINE
| ID: mdl-17701545
ABSTRACT
Protein motions are complex and a good way to describe them is in terms of a very high-dimensional conformation space. We give here a simple explanation of the conformation space and the energy landscape, the conformational motions and protein reactions, based on an analogy to a traffic problem. The analogy provides insight into the slaving of protein processes to bulk solvent fluctuations, in both the native and unfolded states.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Solventes
/
Proteínas
Idioma:
En
Revista:
IUBMB Life
Asunto de la revista:
BIOLOGIA MOLECULAR
/
BIOQUIMICA
Año:
2007
Tipo del documento:
Article
País de afiliación:
Estados Unidos