Modified cold pressor test by cold application to the foot after spinal cord injury: suggestion of hemodynamic control by the spinal cord.
Am J Phys Med Rehabil
; 86(11): 875-82, 2007 Nov.
Article
en En
| MEDLINE
| ID: mdl-18049135
ABSTRACT
OBJECTIVE:
Study hemodynamic responses to cold application to the foot (CAF) to explore the autonomic cardiovascular control by the spinal cord.DESIGN:
Controlled experimental study. Hemodynamic variables were measured or calculated for 13 healthy subjects, 10 patients with traumatic T4-T6 paraplegia, and 11 patients with traumatic C4-C7 tetraplegia. Subjects were continuously monitored for heart rate (HR), blood pressure (BP), and cerebral blood-flow velocity (CBFV) from 5 mins before to 5 mins after 40-120 secs of CAF by ice water foot immersion. The recorded signals were digitized online and analyzed offline in the time and frequency domains.RESULTS:
During CAF, HR increased in the control group but decreased in patients (P < 0.001). BP increased significantly in the control and tetraplegia groups (P < 0.001) and nonsignificantly in the paraplegia group. HR and BP spectral components (LF, HF, LF/HF) did not change significantly. CBFV increased significantly in the patient groups (P < 0.05) but not in the control subjects. The cerebrovascular resistance increased significantly in the control and tetraplegia groups (P < 0.001), but not in the paraplegia group.CONCLUSIONS:
The findings support the presence of hemodynamic autonomic control by the spinal cord and show that responses to CAF can be used to assess its integrity.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Paraplejía
/
Cuadriplejía
/
Traumatismos de la Médula Espinal
/
Frío
/
Hemodinámica
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Am J Phys Med Rehabil
Asunto de la revista:
MEDICINA FISICA
/
REABILITACAO
Año:
2007
Tipo del documento:
Article
País de afiliación:
Israel