Antimicrobial activity of Mahonia aquifolium and two of its alkaloids against oral bacteria.
Schweiz Monatsschr Zahnmed
; 117(11): 1126-31, 2007.
Article
en En
| MEDLINE
| ID: mdl-18072463
ABSTRACT
Extracts or alkaloids isolated from Mahonia aquifolium exhibit antimicrobial activity against Gram-positive and Gram-negative bacteria, fungi, and protozoa. In this study the bacteriostatic and bacteriocidal activities of a M. aquifolium extract and two of its major alkaloids, berberine chloride and oxyacanthine sulphate, were tested in vitro against nine different oral bacteria. Minimum inhibitory concentrations were in the range from < or = 0.0031% to 0.1993% for the M. aquifolium extract, from 0.002% to > 0.125% for berberine chloride, and from 0.0156% to > 0.0625% for oxyacanthine sulphate. The values for the minimum bactericidal concentrations were in the same range, indicating that the test substances most probably acted in a bactericidal manner. The most susceptible bacterium against all three test substances was Porphyromonas gingivalis.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Bacterias
/
Berberina
/
Extractos Vegetales
/
Mahonia
/
Isoquinolinas
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Schweiz Monatsschr Zahnmed
Año:
2007
Tipo del documento:
Article
País de afiliación:
Suiza