[Topical steroid injection for refractory oral chronic graft-versus-host disease].
Rinsho Ketsueki
; 48(11): 1508-10, 2007 Nov.
Article
en Ja
| MEDLINE
| ID: mdl-18080511
ABSTRACT
The standard treatment for refractory oral chronic graft versus host disease (GVHD) has not been established. We present a case of AML accompanied by oral chronic GVHD in a 55-year-old man after allogeneic stem cell transplantation. The stomatitis of the patient was prolonged for a year and resistant to standard immunosuppressant therapy, including systemic administration of prednisolone and tacrolimus; however, local injection of 0.2% dexamethasone (0.5 mg per cm2) into the ulcerative area was drastically effective in improving refractory mucositis and mitigated a vicious cycle of mucosal damage and poor oral hygiene.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Estomatitis
/
Dexametasona
/
Enfermedad Injerto contra Huésped
Límite:
Humans
/
Male
/
Middle aged
Idioma:
Ja
Revista:
Rinsho Ketsueki
Año:
2007
Tipo del documento:
Article
País de afiliación:
Japón