[Hereditary ataxias, spastic parapareses and neuropathies in Eastern Canada]. / Ataxies, paraparésies spastiques et neuropathies héréditaires fréquentes dans l'Est du Canada.
Rev Neurol (Paris)
; 164(1): 12-21, 2008 Jan.
Article
en Fr
| MEDLINE
| ID: mdl-18342054
ABSTRACT
It has been demonstrated, for many inherited diseases, that historical events have shaped the various regional gene pools of Eastern Canada. In so doing, it has given rise to the increased prevalence of some rare diseases due, to founder effects. The following neurogenetic disorders were first identified in patients from Eastern Canada AOA-2, Arsacs, HSN-2, Arca-1, HMSN/ACC and Arsal. The population of Eastern Canada, we are convinced, will still allow the identification of new rare forms of hereditary ataxias, spastic parapareses and neuropathies as well as contribute to the uncovering of their mutated genes. We have summarized our current knowledge of the various hereditary ataxias, spastic parapareses and neuropathies in Eastern Canada. The study of the more common and homogenous features of these diseases has been largely completed.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neuropatía Hereditaria Motora y Sensorial
/
Degeneraciones Espinocerebelosas
/
Paraparesia Espástica
Tipo de estudio:
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
País/Región como asunto:
America do norte
Idioma:
Fr
Revista:
Rev Neurol (Paris)
Año:
2008
Tipo del documento:
Article
País de afiliación:
Canadá