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Prostate small cell carcinoma and skin metastases: a rare entity.
Yildirim, Yesim; Akcay, Yesim; Ozyilkan, Ozgur; Celasun, Bulent.
Afiliación
  • Yildirim Y; Department of Medical Oncology, Baskent University, Ankara, Turkey. dryesimyildirim@yahoo.com
Med Princ Pract ; 17(3): 250-2, 2008.
Article en En | MEDLINE | ID: mdl-18408396
OBJECTIVES: To report a rare case of small cell carcinoma of the prostate with unusual skin metastasis. CLINICAL PRESENTATION AND INTERVENTIONS: A 60-year-old was evaluated for difficulty in urinating. Abdominal computed tomography scans revealed a prostatic mass invading the surrounding tissues and multiple perirectal, periprostatic, para-aortic and pericaval lymph nodes. Needle biopsy specimens showed both small cell carcinoma and adenocarcinoma. He was treated with combination chemotherapy: cisplatin and etoposide and bilateral orchiectomy. After six cycles of the chemotherapy, disease progressed and the patient did not respond to salvage therapy; hence, palliative care was instituted. During the follow-up, papillary lesions were observed in the scrotal skin; biopsy showed metastatic small cell carcinoma. CONCLUSION: Small cell carcinoma of the prostate is an aggressive disease with a highly metastatic potential; but skin metastases are very uncommon. It has poor prognosis despite therapy. Management resembles that of small cell carcinoma of the lung.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Neoplasias Cutáneas / Protocolos de Quimioterapia Combinada Antineoplásica / Carcinoma de Células Pequeñas Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans / Male / Middle aged Idioma: En Revista: Med Princ Pract Asunto de la revista: EDUCACAO Año: 2008 Tipo del documento: Article País de afiliación: Turquía

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Neoplasias Cutáneas / Protocolos de Quimioterapia Combinada Antineoplásica / Carcinoma de Células Pequeñas Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans / Male / Middle aged Idioma: En Revista: Med Princ Pract Asunto de la revista: EDUCACAO Año: 2008 Tipo del documento: Article País de afiliación: Turquía
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