Fully orthogonally protected 2-deoxystreptamine from kanamycin.
J Org Chem
; 73(13): 5131-4, 2008 Jul 04.
Article
en En
| MEDLINE
| ID: mdl-18522414
ABSTRACT
A fully orthogonally protected and enantiopure 2-deoxystreptamine derivative is prepared in a few straightforward steps from commercially available kanamycin. Resolution of a sterically hindered diacetate was effected by a Verenium esterase and was followed by a chemoselective Staudinger reduction-acylation protocol.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Kanamicina
Idioma:
En
Revista:
J Org Chem
Año:
2008
Tipo del documento:
Article
País de afiliación:
Países Bajos
