Case of chromoblastomycosis appearing in an Okinawa patient with a medical history of Hansen's disease.
J Dermatol
; 35(6): 354-61, 2008 Jun.
Article
en En
| MEDLINE
| ID: mdl-18578713
ABSTRACT
Chromoblastomycosis is one of several chronic infectious skin diseases caused by various species of dematiaceous fungi. It is clinically characterized by verrucous skin eruptions and occurs most commonly in tropical and subtropical regions. In Okinawa, a subtropical area, there have been only three reported cases of chromoblastomycosis including the present one. Direct microscopic examination of crust specimens and findings of sclerotic cells in histopathology can confirm the diagnosis, and cultures of crust and/or tissue specimens can identify the causative fungi. We herein report the third case of chromoblastomycosis in Okinawa; it arose in an 87-year-old Japanese woman with a history of Hansen's disease, who lived in a leprosarium in Miyako Island. To identify the causative agent as Fonsecaea pedrosoi, we used the polymerase chain reaction and direct sequencing analysis in addition to the usual methods, which include 20% potassium hydroxide microscopy, histopathological confirmation of sclerotic cells by periodic acid-Schiff stain, culture by Sabouraud's glucose agar, slide culture method, and observation of conidia by scanning electron microscopic examination.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
3_ND
Problema de salud:
3_leprosy
/
3_neglected_diseases
Asunto principal:
Ascomicetos
/
Piel
/
Cromoblastomicosis
/
Dermatosis de la Mano
Tipo de estudio:
Prognostic_studies
Límite:
Aged80
/
Female
/
Humans
País/Región como asunto:
Asia
Idioma:
En
Revista:
J Dermatol
Año:
2008
Tipo del documento:
Article
País de afiliación:
Japón