Renal collecting duct carcinoma in a dog.
Vet Pathol
; 45(4): 489-94, 2008 Jul.
Article
en En
| MEDLINE
| ID: mdl-18587095
ABSTRACT
An 8-year-old, male, mongrel dog developed severe cough and anorexia and died within 3 months. Autopsy revealed an invasive grayish-white mass in the right kidney and multiple nodules in the lungs, thoracic wall, and spleen. Histologically, the renal mass and the other nodules were mainly composed of papillotubular structures lined by oval-to-polygonal pleomorphic cells. The cells were reactive with DBA, PNA, and UEA-1 lectins and positive for vimentin but negative for CD10 and high molecular weight cytokeratin. Because of its histological, histochemical, and immunohistochemical similarities with human collecting duct carcinoma (CDC), a diagnosis of renal collecting duct carcinoma with pulmonary, thoracic, and splenic metastases was established. To our knowledge, this is the first case report of CDC in animals.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Carcinoma de Células Renales
/
Enfermedades de los Perros
/
Neoplasias Renales
Límite:
Animals
Idioma:
En
Revista:
Vet Pathol
Año:
2008
Tipo del documento:
Article
País de afiliación:
Japón