[Status of iodine nutrition of children until 1 year: consequences on the thyroid function]. / Statut en iode chez des enfants de moins de 1 an: conséquences sur la fonction thyroïdienne.
Arch Pediatr
; 15(8): 1276-82, 2008 Aug.
Article
en Fr
| MEDLINE
| ID: mdl-18639444
ABSTRACT
INTRODUCTION:
Iodine deficiency remains a major public health problem mainly in least-developed countries but also in many industrialized countries.OBJECTIVES:
The present study aimed at (1) evaluating the status of iodine nutrition of children until 1 year in the North region of France; (2) studying risk factors for iodine deficiency; (3) evaluating relationship between iodine deficiency and thyroid disorders. PATIENTS ANDMETHODS:
This prospective study was conducted between 1st january and 31st May 2005 in the children's hospital of Lille (North of France) and all hospitalized children until the age of 1 year were enrolled. Urinary iodine assessment was obtained for 95 (83%) of the 114 infants hospitalized during the study period and TSH value was also determined in 57 (60%) of these 114 infants.RESULTS:
Median urinary iodine concentration was 328 microg/L (range 12-1580). Twenty-four (25%) of 95 infants had a high urinary iodine excretion (urinary iodine greater than 400 microg/L). Nineteen (20%) of the 95 infants were iodine deficient (urinary iodine less than 100 microg/L) severe iodine deficiency (less than 20 microg/L; n=5; 5%), moderate iodine deficiency (20-49 microg/L; n=6; 6%), mild iodine deficiency (50-99 microg/L; n=8; 8%). No relationship was found between iodine status and the following data age, sex, familial thyroid disease history, term and type of delivery, nutritional status, type of feeding at inclusion, chronic disease, familial socioeconomic status. TSH value was high (greater than 5 microU/mL) in 7 (12%) of the 57 infants. Only 1 of these 7 infants was iodine deficient. Only 1 of the 19 infants with iodine deficiency had a high TSH value.CONCLUSIONS:
Iodine status is not optimal in our population of hospitalized children until the age of 1 year. There is no clear relationship between iodine status and thyroid function.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
1_ASSA2030
Problema de salud:
1_desigualdade_iniquidade
Asunto principal:
Glándula Tiroides
/
Yodo
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Evaluation_studies
/
Observational_studies
/
Risk_factors_studies
Aspecto:
Equity_inequality
Límite:
Female
/
Humans
/
Infant
/
Male
País/Región como asunto:
Europa
Idioma:
Fr
Revista:
Arch Pediatr
Año:
2008
Tipo del documento:
Article
País de afiliación:
Francia