Efficient mapping of Applied Biosystems SOLiD sequence data to a reference genome for functional genomic applications.
Bioinformatics
; 24(23): 2776-7, 2008 Dec 01.
Article
en En
| MEDLINE
| ID: mdl-18842598
ABSTRACT
UNLABELLED Here, we report the development of SOCS (short oligonucleotide color space), a program designed for efficient and flexible mapping of Applied Biosystems SOLiD sequence data onto a reference genome. SOCS performs its mapping within the context of 'color space', and it maximizes usable data by allowing a user-specified number of mismatches. Sequence census functions facilitate a variety of functional genomics applications, including transcriptome mapping and profiling, as well as ChIP-Seq. AVAILABILITY:
Executables, source code, and sample data are available at http//socs.biology.gatech.edu/
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Genoma
/
Análisis de Secuencia por Matrices de Oligonucleótidos
/
Genómica
Idioma:
En
Revista:
Bioinformatics
Asunto de la revista:
INFORMATICA MEDICA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Estados Unidos