Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue.

Chène, Patrick; Rudloff, Joëlle; Schoepfer, Joseph; Furet, Pascal; Meier, Peter; Qian, Zhiyan; Schlaeppi, Jean-Marc; Schmitz, Rita; Radimerski, Thomas

Chène, Patrick; Rudloff, Joëlle; Schoepfer, Joseph; Furet, Pascal; Meier, Peter; Qian, Zhiyan; Schlaeppi, Jean-Marc; Schmitz, Rita; Radimerski, Thomas.

Afiliación

Chène P; Department of Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.
Rudloff J; Department of Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.
Schoepfer J; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Basel, Switzerland.
Furet P; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Basel, Switzerland.
Meier P; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Basel, Switzerland.
Qian Z; Department of Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.
Schlaeppi JM; Biologics Center, Novartis Institutes for BioMedical Research, Basel, Switzerland.
Schmitz R; Biologics Center, Novartis Institutes for BioMedical Research, Basel, Switzerland.
Radimerski T; Department of Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland.

BMC Chem Biol ; 9: 1, 2009 Jan 07.

Article en En | MEDLINE | ID: mdl-19128485

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: BMC Chem Biol Año: 2009 Tipo del documento: Article País de afiliación: Suiza

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