[Mouse gender-related behavioral responses to long-lasting psychoemotional influence].

ABSTRACT

Behavior of male and female inbred mice of C57BL/6J strain was studied after long-lasting psychoemotional influence consisting of forced living with aggressive male separated with a perforated transparent partition in the same cage, and daily presence of males and female during 10-min intermale confrontations behind a partition caused by introducing intact mouse to an aggressive male. In a month, the increased level of anxiety in mice of both genders was revealed in the elevated plus-maze test. However, only females showed a longer time of passive swimming in the Porsolt's test. Under these conditions, females demonstrated some decrease of communication in the partition test. Accordingly, a more expressed behavior response was revealed in females in comparison with males on long-lasting psychoemotional influence.