The clinical spectrum between posterior polymorphous dystrophy and iridocorneal endothelial syndromes.
Optometry
; 80(8): 431-6, 2009 Aug.
Article
en En
| MEDLINE
| ID: mdl-19635434
ABSTRACT
BACKGROUND:
There are many conditions affecting the corneal endothelium with similar clinical appearances, though with different prognoses, management approaches, and pathophysiologic development. CASE A 39-year-old black woman with a previous diagnosis of asymmetric corneal posterior polymorphous dystrophy (PPMD) presented complaining of irritation in the left eye, worsening over the last week. On examination, her left eye had profuse edema and bullous keratopathy overlying a large placoid gray lesion at the level of the endothelium. Gonioscopy of the left eye found evidence of a membranous development extending from the endothelium to the trabecular meshwork. Examination of her right eye found a perfectly clear cornea and a normal angle. The patient subsequently had Chandler's syndrome diagnosed in the left eye, an iridocorneal endothelial (ICE) syndrome, rather than PPMD.DISCUSSION:
PPMD and ICE syndromes present with many similarities; these clinical entities are in fact thought to be variants of the same disease. Unlike PPMD, Chandler's syndrome is unilateral, acquired, and typically symptomatic and progressive. It also characteristically affects middle-age women.CONCLUSION:
Understanding the clinical features of PPMD and ICE syndromes is important in proper diagnosis and management.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Endotelio Corneal
/
Edema Corneal
/
Distrofias Hereditarias de la Córnea
/
Enfermedades del Iris
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Optometry
Asunto de la revista:
OPTOMETRIA
Año:
2009
Tipo del documento:
Article
País de afiliación:
Estados Unidos