Isolation and structural elucidation of euryjanicins B-D, proline-containing cycloheptapeptides from the Caribbean marine sponge Prosuberites laughlini.
J Nat Prod
; 72(9): 1555-62, 2009 Sep.
Article
en En
| MEDLINE
| ID: mdl-19743810
ABSTRACT
Three new cyclic peptides, euryjanicins B (2), C (3), and D (4), have been isolated from the Puerto Rican marine sponge Prosuberites laughlini, and the structures were elucidated by chemical degradation, ESIMS/MS, and extensive 2D NMR methods. When tested against the National Cancer Institute 60 tumor cell line panel, all of the purified isolates displayed weak cytotoxicity.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Péptidos Cíclicos
/
Poríferos
/
Antineoplásicos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
J Nat Prod
Año:
2009
Tipo del documento:
Article