Comparison of fluid types for resuscitation after acute blood loss in mallard ducks (Anas platyrhynchos).
J Vet Emerg Crit Care (San Antonio)
; 19(5): 467-72, 2009 Oct.
Article
en En
| MEDLINE
| ID: mdl-19821888
ABSTRACT
OBJECTIVE:
The purpose of this study was to determine the LD(50) for acute blood loss in mallard ducks (Anas platyrhynchos), compare the mortality rate among 3 fluid resuscitation groups, and determine the time required for a regenerative RBC response.DESIGN:
Prospective study.SETTING:
Medical College of Wisconsin Research facility. ANIMALS Eighteen mallard ducks were included for the LD(50) study and 28 for the fluid resuscitation study.INTERVENTIONS:
Phlebotomy was performed during both the LD(50) and fluid resuscitation studies. Ducks in the fluid resuscitation study received a 5 mL/kg intravenous bolus of crystalloids, hetastarch (HES), or a hemoglobin-based oxygen-carrying solution (HBOCS). MEASUREMENTS AND MAINRESULTS:
The LD(50) for acute blood loss was 60% of total blood volume. This blood volume was removed in the fluid resuscitation study to create a model of acute blood loss. Following fluid administration, 6 birds in the crystalloid group (66%), 4 birds in the HES group (40%), and 2 birds in the HBOCS group (20%) died. No statistical difference in mortality rate was seen among the 3 fluid resuscitation groups. Relative polychromasia evaluated post-phlebotomy demonstrated regeneration starting at 24 hours and continuing through 48 hours.CONCLUSIONS:
The LD(50) for acute blood loss in mallard ducks was 60% of their total blood volume. Although no statistical difference in mortality rate was appreciated among the 3 fluid resuscitation groups, a trend of decreased mortality rate was observed in the HBOCS group. An early regenerative response was apparent following acute blood loss.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hemoglobinas
/
Derivados de Hidroxietil Almidón
/
Patos
/
Fluidoterapia
/
Hemorragia
/
Soluciones Isotónicas
Tipo de estudio:
Observational_studies
Límite:
Animals
Idioma:
En
Revista:
J Vet Emerg Crit Care (San Antonio)
Asunto de la revista:
MEDICINA DE EMERGENCIA
/
MEDICINA VETERINARIA
/
TERAPIA INTENSIVA
Año:
2009
Tipo del documento:
Article
País de afiliación:
Estados Unidos