Conservation and divergence in developmental networks: a view from Drosophila myogenesis.
Curr Opin Cell Biol
; 21(6): 754-60, 2009 Dec.
Article
en En
| MEDLINE
| ID: mdl-19896355
ABSTRACT
Understanding developmental networks has recently been enhanced through the identification of a large number of conserved essential regulators. Interspecies comparisons of the transcriptional networks regulated by these factors are still at a rather early stage, with limited global data available. Here we use the accumulating phenotypic information from multiple species to provide initial insights into the wiring and rewiring of developmental networks, with particular emphasis on myogenesis, a highly conserved developmental process. This review highlights the most recent findings on the transcriptional program driving Drosophila myogenesis and compares this with vertebrates, revealing emerging themes that may be applicable to other developmental contexts.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Regulación del Desarrollo de la Expresión Génica
/
Desarrollo de Músculos
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Drosophila
/
Redes Reguladoras de Genes
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Curr Opin Cell Biol
Año:
2009
Tipo del documento:
Article
País de afiliación:
Alemania