Fluorogen-activating proteins as biosensors of cell-surface proteins in living cells.
Cytometry A
; 77(8): 776-82, 2010 Aug.
Article
en En
| MEDLINE
| ID: mdl-20653017
ABSTRACT
This study explores the general utility of a new class of biosensor that allows one to selectively visualize molecules of a chosen membrane protein that are at the cell surface. These biosensors make use of recently described bipartite fluoromodules comprised of a fluorogen-activating protein (FAP) and a small molecule (fluorogen) whose fluorescence increases dramatically when noncovalently bound by the FAP (Szent-Gyorgyi et al., Nat Biotechnol 2010;00000-000).
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Técnicas Biosensibles
/
Colorantes Fluorescentes
/
Proteínas de la Membrana
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Cytometry A
Año:
2010
Tipo del documento:
Article
País de afiliación:
Estados Unidos