[Role of immunologic abnormality in recurrent parotitis in children].
Zhejiang Da Xue Xue Bao Yi Xue Ban
; 39(4): 419-23, 2010 07.
Article
en Zh
| MEDLINE
| ID: mdl-20731044
ABSTRACT
OBJECTIVE:
To investigate the relationship between immune function and the recurrent parotitis (RP) for children.METHODS:
The children diagnosed as RP were divided into two groups aged under 6y and over 6y and the immune function were measured and compared with that of normal children.RESULTS:
For RP children the ratio of CD4+ T cell in over 6y group was significantly lower than that in under 6y group (P<0.05), while IgG value in over 6y group was higher than that in under 6y group (P<0.05). Compared with normal children, RP children in under 6y group had higher CD8+ T cell ratio and IgG, IgE, IgA and C3 value (P<0.01) and lower CD4+ T cell ratio (P<0.01), while RP children over 6y group, they had higher CD8+ T cell ratio, IgE value (P<0.01) and C3 (P<0.05), lower CD4<T cell ratio than those in control group (P<0.01). IgE value and CD8+ T cell ratio in under 6y group were higher than those over 6y control group (P<0.01).CONCLUSION:
Impaired immune function may play an important role in the recurrent parotitis in children.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Parotiditis
/
Inmunoglobulina G
/
Relación CD4-CD8
Límite:
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Idioma:
Zh
Revista:
Zhejiang Da Xue Xue Bao Yi Xue Ban
Asunto de la revista:
MEDICINA
Año:
2010
Tipo del documento:
Article
País de afiliación:
China