Functional promoter polymorphism of the neuronal isoform of tryptophan hydroxylase (Tph2) in suicide.
Psychiatry Res
; 186(2-3): 446-7, 2011 Apr 30.
Article
en En
| MEDLINE
| ID: mdl-20869124
ABSTRACT
The association between suicide and G-703T polymorphism of the tryptophan hydroxylase 2 (TPH2), the rate-limiting enzyme in the biosynthesis of the neurotransmitter serotonin, was studied in a sample of 291 suicide victims and 280 healthy subjects of Croatian origin. No significant differences were found between the groups. Obtained results do not support involvement of the investigated polymorphism in the susceptibility to suicide completion.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Polimorfismo Genético
/
Suicidio
/
Triptófano Hidroxilasa
/
Regiones Promotoras Genéticas
/
Conducta Autodestructiva
Tipo de estudio:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
Psychiatry Res
Año:
2011
Tipo del documento:
Article
País de afiliación:
Croacia