Phase I study of combination recombinant interleukin-2 and interferon gamma in patients with advanced malignancies.
Mol Biother
; 2(2): 96-103, 1990 Jun.
Article
en En
| MEDLINE
| ID: mdl-2114123
ABSTRACT
A phase I trial of interleukin-2 and interferon gamma combination treatment in patients with advanced malignancies was performed based on preclinical in vitro and in vivo data which demonstrated synergistic antitumor effect. The toxicities, immune parameters, and tumor responses are described. The clinical and biologic maximal tolerated doses were extrapolated from these data.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Protocolos de Quimioterapia Combinada Antineoplásica
/
Interferón gamma
/
Interleucina-2
/
Neoplasias
Límite:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Mol Biother
Asunto de la revista:
ALERGIA E IMUNOLOGIA
/
NEOPLASIAS
/
TERAPEUTICA
Año:
1990
Tipo del documento:
Article