In vitro studies of biomedical magnesium alloys in a simulated physiological environment: a review.
Acta Biomater
; 7(4): 1452-9, 2011 Apr.
Article
en En
| MEDLINE
| ID: mdl-21145436
ABSTRACT
In spite of the immense potential of biodegradable magnesium alloys, the fast degradation rates of Mg-based biomedical implants in the physiological environment impose severe limitations in many clinical applications. Consequently, extensive in vitro studies have been carried out to investigate the materials' performance and fathom the associated mechanisms. Here, an up-to-date review of the in vitro studies on biomedical magnesium alloys in a simulated physiological environment is provided. This review focuses on four topics (1) materials selection and in vitro biocompatibility of biomedical magnesium alloys; (2) in vitro degradation of biomedical magnesium alloys in simulated physiological environments, specifically discussing corrosion types, degradation rates, corrosion products and impact of the constituents in body fluids on materials degradation; (3) selection of suitable test media for in vitro assessment; and (4) future research trends.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Materiales Biocompatibles
/
Líquidos Corporales
/
Ensayo de Materiales
/
Aleaciones
/
Magnesio
Límite:
Humans
Idioma:
En
Revista:
Acta Biomater
Año:
2011
Tipo del documento:
Article
País de afiliación:
China