Parvalbumin-positive CA1 interneurons are required for spatial working but not for reference memory.
Nat Neurosci
; 14(3): 297-9, 2011 Mar.
Article
en En
| MEDLINE
| ID: mdl-21278730
ABSTRACT
Parvalbumin-positive GABAergic interneurons in cortical circuits are hypothesized to control cognitive function. To test this idea directly, we functionally removed parvalbumin-positive interneurons selectively from hippocampal CA1 in mice. We found that parvalbumin-positive interneurons are dispensable for spatial reference, but are essential for spatial working memory.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Parvalbúminas
/
Hipocampo
/
Interneuronas
/
Memoria a Corto Plazo
Límite:
Animals
Idioma:
En
Revista:
Nat Neurosci
Asunto de la revista:
NEUROLOGIA
Año:
2011
Tipo del documento:
Article
País de afiliación:
Reino Unido
