[Effects of organic selenium substance, selenomethionine, in acute alcohol intoxication].

The effect of the preliminary saturation of rats with selenomethionine (50 g/kg, intragastrically, daily, 10 days) prior to acute alcohol intoxication (5 g/kg, 20% ethanol solution, intragastrically, singly on the 11th day with the exposure for 2 hours) was investigated. The activities of glutathione peroxidases (gastrointestinal mucosa, blood plasma, erythrocytes, liver), the levels of oxidized and reduced glutathione, LPO intensity and blood corticosterone level were studied.