Novel taxa-4(20),12-diene and 2(3â20)abeotaxane from needles of Taxus canadensis.
Biosci Biotechnol Biochem
; 75(9): 1698-701, 2011.
Article
en En
| MEDLINE
| ID: mdl-21897043
ABSTRACT
A novel 6/8/6-membered taxane with a rare C-12(13)-double bond and rare 2(3â20)abeotaxane were isolated from the needles of Taxus canadensis. Their structures were characterized as 7ß,9α,10ß-triacetoxytaxa-4(20),12-diene-2α,5α,11ß-triol (1) and 2α,7ß,10ß-triacetoxy-5α-hydroxy-2(3â20)abeotaxa-4(20),11-diene-9,13-dione (2) on the basis of 1D and 2D spectroscopic data. 1 is the first example of a natural taxane without substitution at both C-13 and C-14.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Extractos Vegetales
/
Taxus
/
Taxoides
/
Antineoplásicos
Tipo de estudio:
Incidence_studies
Límite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Biosci Biotechnol Biochem
Asunto de la revista:
BIOQUIMICA
/
BIOTECNOLOGIA
Año:
2011
Tipo del documento:
Article
País de afiliación:
China