Low frequency of Toll-like receptors 2 and 4 gene polymorphisms in Mexican patients and their association with type 2 diabetes.
Int J Immunogenet
; 38(6): 519-23, 2011 Dec.
Article
en En
| MEDLINE
| ID: mdl-21902816
Type 2 diabetes (T2D) is characterized by a chronic low-grade inflammatory state. SNP in Toll-like receptor (TLR) genes has been associated with impaired inflammatory response. We genotyped the TLR4/D299G, TLR4/T399I and TLR2/R753Q polymorphisms. Low frequency was found with no association with T2D, nevertheless the TLR2 SNP was associated with lower levels in HDL-cholesterol values.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Predisposición Genética a la Enfermedad
/
Polimorfismo de Nucleótido Simple
/
Diabetes Mellitus Tipo 2
/
Receptor Toll-Like 2
/
Receptor Toll-Like 4
/
Estudios de Asociación Genética
/
Frecuencia de los Genes
Tipo de estudio:
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Male
País/Región como asunto:
Mexico
Idioma:
En
Revista:
Int J Immunogenet
Asunto de la revista:
ALERGIA E IMUNOLOGIA
/
GENETICA
Año:
2011
Tipo del documento:
Article
