Unusual case of proximal calciphylaxis without renal failure.
J Cutan Med Surg
; 15(5): 290-2, 2011.
Article
en En
| MEDLINE
| ID: mdl-21962190
ABSTRACT
BACKGROUND:
Calciphylaxis is a rare syndrome of vascular calcification with subsequent cutaneous and tissue necrosis. It usually manifests as a complication of end-stage renal failure, affecting 1 to 4% of long-term dialysis patients. Very exceptionally, it can occur without chronic renal failure.OBJECTIVE:
The goal of this study was to discuss an exceptional case of extensive calciphylaxis in the absence of chronic renal failure and its successful management.METHODS:
We present a case of a 31-year-old woman with extensive proximal, ulcerated calciphylaxis without associated chronic renal failure. Our patient had quite a few risk factors associated with the pathogenesis of calciphylaxis, such as obesity, malnutrition, and a transient episode of acute renal failure.RESULTS:
She was successfully treated with sodium thiosulfate, extensive wound débridement (more than 30% total body surface), and subsequent skin grafts. The patient has miraculously survived this often fatal condition.CONCLUSION:
Calciphylaxis can occur even in the absence of chronic renal failure. This often fatal condition can be managed successfully with a combination of aggressive wound control and the fairly newly described sodium thiosulfate therapy.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Piel
/
Calcifilaxia
Tipo de estudio:
Etiology_studies
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
J Cutan Med Surg
Asunto de la revista:
DERMATOLOGIA
Año:
2011
Tipo del documento:
Article
País de afiliación:
Canadá