[HIV infection and chronic inflammation: is the bacterial translocation the underlying cause?]. / Infección por el virus de la inmunodeficiencia humana tipo 1 e inflamación persistente: ¿es la traslocación bacteriana la causa oculta?
Med Clin (Barc)
; 138(15): 673-7, 2012 May 26.
Article
en Es
| MEDLINE
| ID: mdl-22364956
ABSTRACT
Currently, non-AIDS comorbidities (cardiovascular disease, non-AIDS-related cancers, liver disease, osteoporosis, etc.) have become an important cause of morbimortality in patients with human immunodeficiency virus type 1 (HIV-1) infection. The elevation of plasma markers of inflammation has been associated with the development of cardiovascular disease and death from all causes. Therefore, there is great interest in elucidating the underlying causes responsible for this persistent inflammatory status. The intestinal barrier disruption associated with HIV-1 infection may favor the passage of gut microbial products into the blood, resulting in immune stimulation. In this article we review the pathogenesis of bacterial translocation and its relevance to HIV-1 infection.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
2_ODS3
Problema de salud:
2_enfermedades_transmissibles
Asunto principal:
Infecciones por VIH
/
VIH-1
/
Traslocación Bacteriana
/
Inflamación
Tipo de estudio:
Etiology_studies
Límite:
Humans
Idioma:
Es
Revista:
Med Clin (Barc)
Año:
2012
Tipo del documento:
Article