Current status of hematopoietic stem cell transplantation for acute radiation syndromes.
Int J Hematol
; 95(3): 227-31, 2012 Mar.
Article
en En
| MEDLINE
| ID: mdl-22382644
ABSTRACT
Many people believe that hematopoietic stem cell transplantation (HSCT) together with various hematopoietic factors may aid or rescue victims of acute radiation exposure. However, nearly all patients who have received current HSCT for severe bone marrow damage in the past died relatively shortly after transplantation, even when engraftment followed by autologous blood cell recovery was observed. The causes of death in such cases involved rapidly progressing insults to many non-hematopoietic tissues, such as lung and gut, potentially exacerbated by the conditioning regimen and immune dysfunction. We should recognize that at present avoiding high-dose radiation exposure is the only safe option.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
1_ASSA2030
/
5_ODS3_mortalidade_materna
Problema de salud:
1_surtos_doencas_emergencias
/
5_violence_disasters
Asunto principal:
Trasplante de Células Madre Hematopoyéticas
/
Síndrome de Radiación Aguda
Límite:
Humans
Idioma:
En
Revista:
Int J Hematol
Asunto de la revista:
HEMATOLOGIA
Año:
2012
Tipo del documento:
Article
País de afiliación:
Japón