Acral peeling skin syndrome in two East-African siblings: case report.
BMC Dermatol
; 12: 2, 2012 Mar 19.
Article
en En
| MEDLINE
| ID: mdl-22429841
ABSTRACT
BACKGROUND:
Acral peeling skin syndrome is a rare autosomal recessive genodermatosis due to a missense mutation in transglutaminase 5. The skin peeling occurs at the separation of the stratum corneum from the stratum granulosum. CASE PRESENTATION We present a case of two siblings who developed continuous peeling of the palms and soles from the first year of life. This peeling was more severe on the soles than palms and on younger sibling than elder sibling. Peeling is worsened by occlusion and sweating.CONCLUSIONS:
Sporadic cases of Acral Peeling Skin Syndrome occur in African population. There is variability in time of presentation and clinical severity even within families.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trastornos de la Pigmentación
/
Dermatitis Exfoliativa
/
Dermatosis del Pie
/
Dermatosis de la Mano
Límite:
Adolescent
/
Child
/
Female
/
Humans
/
Male
País/Región como asunto:
Africa
Idioma:
En
Revista:
BMC Dermatol
Asunto de la revista:
DERMATOLOGIA
Año:
2012
Tipo del documento:
Article
País de afiliación:
Tanzania