The STF2p hydrophilin from Saccharomyces cerevisiae is required for dehydration stress tolerance.
PLoS One
; 7(3): e33324, 2012.
Article
en En
| MEDLINE
| ID: mdl-22442684
ABSTRACT
The yeast Saccharomyces cerevisiae is able to overcome cell dehydration; cell metabolic activity is arrested during this period but restarts after rehydration. The yeast genes encoding hydrophilin proteins were characterised to determine their roles in the dehydration-resistant phenotype, and STF2p was found to be a hydrophilin that is essential for survival after the desiccation-rehydration process. Deletion of STF2 promotes the production of reactive oxygen species and apoptotic cell death during stress conditions, whereas the overexpression of STF2, whose gene product localises to the cytoplasm, results in a reduction in ROS production upon oxidative stress as the result of the antioxidant capacity of the STF2p protein.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
6_ODS3_enfermedades_notrasmisibles
Problema de salud:
6_endocrine_disorders
Asunto principal:
Saccharomyces cerevisiae
/
Especies Reactivas de Oxígeno
/
Citoplasma
/
Proteínas de Saccharomyces cerevisiae
/
Deshidratación
/
Antioxidantes
Idioma:
En
Revista:
PLoS One
Asunto de la revista:
CIENCIA
/
MEDICINA
Año:
2012
Tipo del documento:
Article
País de afiliación:
España