Intracerebroventricular injection of orexin-2 receptor antagonist promotes REM sleep.
Behav Brain Res
; 237: 59-62, 2013 Jan 15.
Article
en En
| MEDLINE
| ID: mdl-22989413
Orexins are important regulators of sleep-wakefulness (S-W). Rats were intracerebroventricularly (ICV) administered selective orexin-2 receptor antagonist, TCS-OX2-29. There was decreased wakefulness due to a decrease in the average wake episode duration and an increased REM sleep due to an increase in the number of REM episodes, indicating an inhibitory role of the central orexin-2 receptors on REM sleep generation.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Piridinas
/
Sueño REM
/
Receptores de Neuropéptido
/
Receptores Acoplados a Proteínas G
/
Isoquinolinas
Límite:
Animals
Idioma:
En
Revista:
Behav Brain Res
Año:
2013
Tipo del documento:
Article
País de afiliación:
India
