[Binding of human serum low-density lipoprotein cholesterol in vitro by sulfated pectin derivatives].
Bioorg Khim
; 38(3): 365-9, 2012.
Article
en Ru
| MEDLINE
| ID: mdl-22997708
ABSTRACT
The ability to bind human serum LDL-C in vitro by the native pectins is lower than that of their sulfation derivatives. The number of sulfate groups and molecular weight of the sulfated derivatives are assumed to be crucial factors. The sulfated derivatives of pectin with molecular weight above 200 kDa containing 45 wt % sulfate groups possess the highest ability to bind atherogenic lipids, the lowest activity was estimated for the derivatives with molecular weight below 50 kDa containing 5 wt % of sulfate groups.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Sulfatos
/
Pectinas
/
LDL-Colesterol
Límite:
Animals
/
Humans
Idioma:
Ru
Revista:
Bioorg Khim
Año:
2012
Tipo del documento:
Article