Novel far-visible and near-infrared pH probes based on styrylcyanine for imaging intracellular pH in live cells.

Fan, Li; Fu, Yue-Jun; Liu, Qiao-Ling; Lu, Dong-Tao; Dong, Chuan; Shuang, Shao-Min

Fan, Li; Fu, Yue-Jun; Liu, Qiao-Ling; Lu, Dong-Tao; Dong, Chuan; Shuang, Shao-Min.

Afiliación

Fan L; College of Chemistry and Chemical Engineering, Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan 030006, PR China.

Chem Commun (Camb) ; 48(91): 11202-4, 2012 Nov 25.

Article en En | MEDLINE | ID: mdl-23047294

ABSTRACT

ABSTRACT

Two novel vis-NIR pH probes based on styrylcyanine with acidic pH response are easily synthesized, which display large Stokes shift and high sensitivity. The significant colocalizations of two probes with LysoTracker Green DND-26 are achieved in C6 cells, suggesting potential application for imaging acidic organelles in live cells.

Asunto(s)

Carbocianinas/química; Colorantes Fluorescentes/química; Línea Celular Tumoral; Humanos; Concentración de Iones de Hidrógeno; Microscopía Confocal; Espectroscopía Infrarroja Corta

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carbocianinas / Colorantes Fluorescentes Límite: Humans Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2012 Tipo del documento: Article

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