Controversies in granzyme biology.
Tissue Antigens
; 80(6): 477-87, 2012 Dec.
Article
en En
| MEDLINE
| ID: mdl-23137319
ABSTRACT
Granzymes (Grz) are a family of serine proteases found in the granules of cytotoxic lymphocytes and are emerging as an important group of proteins involved in immune function and surveillance. Grz have both cytotoxic and more recently reported non-cytotoxic roles, however these functions are still subject to thorough investigation. The significance of the cytotoxic and importantly the non-cytotoxic roles of Grz will be discussed in this review, detailing accepted and controversial functions.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Granzimas
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Tissue Antigens
Año:
2012
Tipo del documento:
Article
País de afiliación:
Australia