Successful management of a possible antibiotic-related acquired factor V inhibitor: a case report and review of the literature.
Acta Haematol
; 129(3): 182-4, 2013.
Article
en En
| MEDLINE
| ID: mdl-23257771
ABSTRACT
Acquired factor inhibitors are rare. We report a case of an elderly male who presented with a bleeding diathesis associated with an elevated prothrombin time and an activated partial thromboplastin time. Work-up revealed undetectable factor V activity and a factor V inhibitor level of >50 Bethesda units. The inhibitor may have been triggered by antibiotics. With a multimodality approach using steroids, platelet transfusions, intravenous immunoglobulin, factor VIII inhibitor bypass activity agent and cyclophosphamide, we successfully eliminated the inhibitor and controlled the bleeding.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Factor V
/
Inhibidores de Factor de Coagulación Sanguínea
/
Hemorragia
/
Antibacterianos
Límite:
Aged80
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Acta Haematol
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos