Novel polyomaviral infection in the placenta of a northern fur seal (Callorhinus ursinus) on the Pribilof Islands, Alaska, USA.
J Wildl Dis
; 49(1): 163-7, 2013 Jan.
Article
en En
| MEDLINE
| ID: mdl-23307383
ABSTRACT
Viruses of the family Polyomaviridae infect a wide variety of avian and mammalian hosts with a broad spectrum of outcomes including asymptomatic infection, acute systemic disease, and tumor induction. In 2010, intranuclear viral inclusion bodies were identified in trophoblasts of a single northern fur seal (NFS; Callorhinus ursinus) placenta from a presumed healthy birth on St. Paul Island, Alaska. On transmission electron microscopy, virions were approximately 40 nm in diameter and were arranged in paracrystalline arrays within the nucleus. The tissue was positive for the polyomaviral major capsid gene (VP1) by PCR, and the sequenced product revealed a novel Orthopolyomavirus. Twenty-nine additional NFS placentas, devoid of viral inclusions on histologic examination, were tested for polyomavirus by PCR; all were negative. The significance of this novel virus for the infected animal is unknown, but the virus does not appear to be very prevalent within the placentas from newborn northern fur seal pups.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Placenta
/
Complicaciones Infecciosas del Embarazo
/
Infecciones Tumorales por Virus
/
Poliomavirus
/
Infecciones por Polyomavirus
/
Lobos Marinos
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Pregnancy
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Wildl Dis
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos